A Brief Tour of the Development of Senolytic Therapies to Clear Senescent Cells – Fight Aging!

[ad_1] Senescent cells accumulate with age as the immune system falters in its ability to clear these cells in a timely fashion. Senolytic therapies selectively destroy some fraction of senescent cells, and first generation senolytic drugs have been demonstrated to rapidly and impressively reverse age-related disease and extend life in mice. The best of … Read more

Correlations with Mortality in Levels of Proteins Secreted by Senescent Cells – Fight Aging!

[ad_1] Here, researchers investigate correlations between late life mortality and levels of specific proteins produced by senescent cells as a part of the senescence-associated secretory phenotype (SASP). While looking over the paper, it is worth bearing in mind that circulating levels of many of the molecules thought to be important components of the SASP … Read more