Lowered Iron Levels in Hematopoietic Stem Cells Reverse Some Age-Related Dysfunction – Fight Aging!

[ad_1] Lowered Iron Levels in Hematopoietic Stem Cells Reverse Some Age-Related Dysfunction Researchers here report on a way to reverse some of the age-related dysfunction observed in the hematopoietic stem cell population resident in bone marrow. These cells are responsible for generating red blood cells and immune cells. Some fraction of the age-related decline … Read more

Is the Aging Hippocampus Particularly Vulnerable to Blood-Brain Barrier Dysfunction? – Fight Aging!

[ad_1] The hippocampus in the brain is vital to cognitive functions involving learning and memory. In today’s open access paper, researchers review the evidence for the hippocampus to be particularly vulnerable to damaging mechanisms, including those involved in aging. It is tentatively suggested that physiological and biochemical differences in the hippocampus point to a … Read more

Cellular Senescence in the Aging and Dysfunction of Skin – Fight Aging!

[ad_1] A great deal of research and development effort is now focused on finding ways to reduce the contribution of senescent cells to degenerative aging. Initiatives range from fundamental research into the biochemistry of senescent cells to clinical trials of early senolytic therapies capable of selectively destroying senescent cells. A growing burden of senescent … Read more

Reviewing the Contributions of Circadian Rhythm Dysfunction and Dysbiosis to Blood-Brain Barrier Leakage – Fight Aging!

[ad_1] The blood-brain barrier is a layer of specialized cells wrapping blood vessels that pass through the brain. Only certain molecules and cells are admitted. The metabolism of the brain is thus isolated from that of the rest of the body. In particular, the immune system of the brain is quite different from that … Read more