Lowered Iron Levels in Hematopoietic Stem Cells Reverse Some Age-Related Dysfunction Researchers here report on a way to reverse some of the age-related dysfunction observed in the hematopoietic stem cell population resident in bone marrow. These cells are responsible for generating red blood cells and immune cells. Some fraction … Read more
The hippocampus in the brain is vital to cognitive functions involving learning and memory. In today’s open access paper, researchers review the evidence for the hippocampus to be particularly vulnerable to damaging mechanisms, including those involved in aging. It is tentatively suggested that physiological and biochemical differences in the … Read more
A great deal of research and development effort is now focused on finding ways to reduce the contribution of senescent cells to degenerative aging. Initiatives range from fundamental research into the biochemistry of senescent cells to clinical trials of early senolytic therapies capable of selectively destroying senescent cells. A … Read more
The blood-brain barrier is a layer of specialized cells wrapping blood vessels that pass through the brain. Only certain molecules and cells are admitted. The metabolism of the brain is thus isolated from that of the rest of the body. In particular, the immune system of the brain is … Read more