Loss of TRIO Expression at Neuromuscular Junctions Precedes Age-Related Loss of Motor Function – Fight Aging!

[ad_1] Many mechanisms are thought to contribute to the age-related decline of muscle mass and strength, but there are the usual debates over which are more important, which are the primary causes, and how they relate to one another. Little of our biochemistry is as fully understood as we … Read more

Age-Related Frailty, a Case of All Too Little Prevention – Fight Aging!

[ad_1] One of the interesting points made in today’s open access review paper is that there is a lack of research into the early manifestations and prevention of frailty. According to the authors, it was only recently the case that the research community established that meaningful levels of pre-frailty … Read more

Low Serum α-Klotho Correlates with Raised Risk of Age-Related Mortality – Fight Aging!

[ad_1] Klotho is one of the few longevity-associated genes shown to work in both directions; lower expression shortens life span in animal studies, while increased expression modestly slows aging. Despite several decades of research, scientists have yet to reach a full understanding of how klotho influences life span. The … Read more

State of Physical Fitness is a Reliable Predictor of Age-Related Mortality – Fight Aging!

[ad_1] State of Physical Fitness is a Reliable Predictor of Age-Related Mortality Being more physically fit at a given age reliably correlates with a lower future mortality risk. While human epidemiological data can only provide correlations, animal studies can and do provide evidence for physical fitness and exercise to … Read more

Lowered Iron Levels in Hematopoietic Stem Cells Reverse Some Age-Related Dysfunction – Fight Aging!

[ad_1] Lowered Iron Levels in Hematopoietic Stem Cells Reverse Some Age-Related Dysfunction Researchers here report on a way to reverse some of the age-related dysfunction observed in the hematopoietic stem cell population resident in bone marrow. These cells are responsible for generating red blood cells and immune cells. Some … Read more