[ad_1] Many mechanisms are thought to contribute to the age-related decline of muscle mass and strength, but there are the usual debates over which are more important, which are the primary causes, and how they relate to one another. Little of our biochemistry is as fully understood as we might like it to be, … Read more
[ad_1] One of the interesting points made in today’s open access review paper is that there is a lack of research into the early manifestations and prevention of frailty. According to the authors, it was only recently the case that the research community established that meaningful levels of pre-frailty exist in middle-age. Further, while … Read more
[ad_1] Today’s open access review paper goes back to the basics on aging and cancer, a first principles consideration of whether or not the evidence shows that we should think of cancer as a distinct process from aging. It is certainly the case that while cancer incidence increases with age, it doesn’t keep on … Read more
[ad_1] Klotho is one of the few longevity-associated genes shown to work in both directions; lower expression shortens life span in animal studies, while increased expression modestly slows aging. Despite several decades of research, scientists have yet to reach a full understanding of how klotho influences life span. The klotho gene produces a transmembrane … Read more
[ad_1] State of Physical Fitness is a Reliable Predictor of Age-Related Mortality Being more physically fit at a given age reliably correlates with a lower future mortality risk. While human epidemiological data can only provide correlations, animal studies can and do provide evidence for physical fitness and exercise to modestly slow aspects of aging … Read more
[ad_1] Lowered Iron Levels in Hematopoietic Stem Cells Reverse Some Age-Related Dysfunction Researchers here report on a way to reverse some of the age-related dysfunction observed in the hematopoietic stem cell population resident in bone marrow. These cells are responsible for generating red blood cells and immune cells. Some fraction of the age-related decline … Read more