[ad_1] Researchers here identify a mechanism by which the practice of calorie restriction promotes muscle stem cell function, and thus repair and maintenance of muscle tissue. In animal studies calorie restriction is shown to produce both (a) a short-term effect associated with improved regeneration, and (b) a long-term effect in the sense of slowing … Read more
[ad_1] Lowered Iron Levels in Hematopoietic Stem Cells Reverse Some Age-Related Dysfunction Researchers here report on a way to reverse some of the age-related dysfunction observed in the hematopoietic stem cell population resident in bone marrow. These cells are responsible for generating red blood cells and immune cells. Some fraction of the age-related decline … Read more
[ad_1] The balance of microbial populations making up the gut microbiome changes with age in ways that provoke chronic inflammation, as well as reduce production of beneficial metabolites. In recent years, researchers have shown that Alzheimer’s patients exhibit a distinctly dysregulated gut microbiome in comparison to other older individuals. This raises the question of … Read more
[ad_1] The hippocampus in the brain is vital to cognitive functions involving learning and memory. In today’s open access paper, researchers review the evidence for the hippocampus to be particularly vulnerable to damaging mechanisms, including those involved in aging. It is tentatively suggested that physiological and biochemical differences in the hippocampus point to a … Read more
[ad_1] The primary problems with drug development are self-evident from the data. Firstly the process of drug development has become enormously more expensive over the past seventy years, a period in in which rapid technological progress has diminished the cost and effort required for any task in pharmacology and biotechnology by orders of magnitude. … Read more
[ad_1] In the interview noted here, Aubrey de Grey of the Longevity Escape Velocity (LEV) Foundation makes a bold prediction of 12-15 years as to when we might see the advent of the first therapies capable of extending the healthy human life span by a few decades, allowing older people to live long enough … Read more