[ad_1] Oxidative Stress and Cellular Senescence in Alzheimer’s Disease In this paper, the authors discuss the overlap between oxidative stress and growing numbers of senescent cells in the brain. Both are thought to contribute to neurodegenerative conditions such as Alzheimer’s disease. The aging of the brain is complex, a web of interacting processes, causes, … Read more
[ad_1] Should we expect an approach focused on repair of synapses in neurodegenerative conditions like Alzheimer’s disease, while leaving the causative mechanisms of the condition operating intact, to have a large effect on patient outcomes? Given what is known of the underlying mechanisms of protein aggregation, neuroinflammation, and other problems that ultimately kill neurons, … Read more
[ad_1] Thyroid disease and diabetes often go hand in hand, and it’s something you should keep an eye on since thyroid disease can significantly impact your diabetes and your overall well-being. According to the American Thyroid Association (ATA), more than 12 percent of the U.S. population will develop a thyroid condition during their lifetime. Although … Read more
[ad_1] RNA Interference as a Mechanism in Alzheimer’s Disease It presently costs little to assess the transcriptomic state of a cell, the amounts and sequences of various RNA transcripts produced from DNA. Thus a fair amount of research into health, disease, and cell biochemistry is focused on this complex layer of cell behavior. It … Read more
[ad_1] January 11, 2024 Parkinson’s Disease (PD) is a neurodegenerative disorder that primarily affects movement and is characterized by tremors, stiffness, and difficulty with balance and coordination. Beyond the physical symptoms, Parkinson’s can also have a significant impact on one’s mental health. Emotional changes such as depression, stress, apathy, or anxiety can sometimes prove more … Read more
[ad_1] Cells contain many proteasomes, one portion of a broad array of repair and quality control mechanisms. The proteasome is a hollow, capped cylindrical structure made of many component proteins. It admits entry only to proteins that have been decorated with the addition of a ubiquitin molecule. Once inside the proteasome’s central chamber, the … Read more