Interactions Between Innervation, Vascular Aging, and Loss of Capillary Density in the Heart – Fight Aging!

[ad_1] One noted aspect of vascular aging is that the processes of angiogenesis become less effective with age, and as a consequence aged tissues lose capillary density. This harms function by reducing the supply of nutrients and oxygen to energy-hungry tissues such as muscles and brain, as well as putting stress on the remaining … Read more

Fight Aging! Newsletter, January 29th 2024 – Fight Aging!

[ad_1] Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry … Read more

A Tour of Geroscience, Largely Focused on Unambitious Goals in the Treatment of Aging – Fight Aging!

[ad_1] Geroscience is a philosophy of development, suggesting that aging can be slowed and we should work towards means to do so. In practice, geroscience is, more or less, the the name given to that part of the research and development community that aims to produce means to alter metabolism to modestly slow aging. … Read more

RNA Interference as a Mechanism in Alzheimer’s Disease – Fight Aging!

[ad_1] RNA Interference as a Mechanism in Alzheimer’s Disease It presently costs little to assess the transcriptomic state of a cell, the amounts and sequences of various RNA transcripts produced from DNA. Thus a fair amount of research into health, disease, and cell biochemistry is focused on this complex layer of cell behavior. It … Read more

Reviewing the Potential for Klotho as a Basis for Therapy – Fight Aging!

[ad_1] Klotho is one of the few robustly longevity-associated genes discovered over the past few decades. Increased levels of the circulating α-klotho protein slows aging in mice and is associated with better late life health in humans. Additionally, more of this α-klotho appears to slow cognitive aging and also boost cognitive function in younger … Read more

Commentary on Gaps in the Knowledge of Aging – Fight Aging!

[ad_1] There are any number of sizable gaps in the understanding of how aging progresses at the detail level, which processes are more or less important, the direct of causation for many different interactions, and so forth. Aging is very complex because a living organism is very complex. Even simply causes produce complex outcomes … Read more