Lowered Iron Levels in Hematopoietic Stem Cells Reverse Some Age-Related Dysfunction – Fight Aging!

[ad_1] Lowered Iron Levels in Hematopoietic Stem Cells Reverse Some Age-Related Dysfunction Researchers here report on a way to reverse some of the age-related dysfunction observed in the hematopoietic stem cell population resident in bone marrow. These cells are responsible for generating red blood cells and immune cells. Some fraction of the age-related decline … Read more

Towards a Better Understanding of the Role of the Gut Microbiome in Alzheimer’s Disease – Fight Aging!

[ad_1] The balance of microbial populations making up the gut microbiome changes with age in ways that provoke chronic inflammation, as well as reduce production of beneficial metabolites. In recent years, researchers have shown that Alzheimer’s patients exhibit a distinctly dysregulated gut microbiome in comparison to other older individuals. This raises the question of … Read more

Is the Aging Hippocampus Particularly Vulnerable to Blood-Brain Barrier Dysfunction? – Fight Aging!

[ad_1] The hippocampus in the brain is vital to cognitive functions involving learning and memory. In today’s open access paper, researchers review the evidence for the hippocampus to be particularly vulnerable to damaging mechanisms, including those involved in aging. It is tentatively suggested that physiological and biochemical differences in the hippocampus point to a … Read more

A Lengthy View of Everything that is Wrong with the Drug Development Industry – Fight Aging!

[ad_1] The primary problems with drug development are self-evident from the data. Firstly the process of drug development has become enormously more expensive over the past seventy years, a period in in which rapid technological progress has diminished the cost and effort required for any task in pharmacology and biotechnology by orders of magnitude. … Read more

Optimism on the Timeline for Extending Human Lifespans by 20 Years or More – Fight Aging!

[ad_1] In the interview noted here, Aubrey de Grey of the Longevity Escape Velocity (LEV) Foundation makes a bold prediction of 12-15 years as to when we might see the advent of the first therapies capable of extending the healthy human life span by a few decades, allowing older people to live long enough … Read more

Fight Aging! Newsletter, March 11th 2024 – Fight Aging!

[ad_1] Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry … Read more