FOXF1 Gene Therapy Improves Regeneration of Intervertebral Discs Following Injury – Fight Aging!

[ad_1] Intervertebral disc degeneration is a feature of aging, and injury can produce further challenges. A range of approaches have been assessed to enhance the regenerative capacity of disc tissue, useful not just after injury, but also to reverse some of the declines in disc structure and function produced by aging. Stem cell therapies … Read more

Exercise Improves Neurogenesis via Restoration of Microglia to a More Youthful Phenotype – Fight Aging!

[ad_1] Exercise is known to improve cognitive function and neurogenesis, the process by which new neurons are created by neural stem cells and then mature to integrate into existing neural networks. Neurogenesis is best studied in the hippocampus, where it is necessary for learning and memory function to take place. It is also likely … Read more

MiR-145-5p Overexpression Improves Stem Cell Transplantation – Fight Aging!

[ad_1] It is now commonplace for patients to undergo first generation stem cell therapy where the transplanted cells (which may or may not actually be stem cells) are derived from fat tissue. These therapies clearly produce some degree of benefit, primarily suppression of inflammation. There is a high degree of variability of outcomes between … Read more

Senolytic CAR T Cell Therapy Improves Health in Aged Mice – Fight Aging!

[ad_1] Senolytic CAR T Cell Therapy Improves Health in Aged Mice To the degree that senescent cells in a tissue exhibit distinctive surface features, one can deploy technologies such as chimeric antigen receptor T cells to selectively destroy them. T cells will destroy whatever cell binds to the chimeric antigen receptor they are equipped … Read more